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Publications

Steensma Laboratory

Selected Publications

Lane BR, Bissonnette J, Waldherr T, Ritz-Holland D, Chesla D, Cottingham SL, Alberta S, Liu C, Thompson AB, Graveel C, MacKeigan JP, Noyes SL, Smith J, Lakhani N, Steensma MR. In press. Development of a Center for Personalized Cancer Care at a regional cancer center: Feasibility trial of an institutional tumor sequencing advisory board. J Mol Diagn                 PubMed

Pelle DW, Ringler JW, Peacock JD, Kampfschulte K, Scholten DJ 2nd, Davis MD, Mitchell DS, Steensma MR. In press. Targeting receptor-activator nuclear kappa beta ligand in aneurysmal bone cysts: verification of target and therapeutic response.  Transl Res.

Foley JM, Scholten DJ 2nd, Monks N, Cherba D, Monsma D, Davidson P, Dylewski D, Dykema K, Winn M, Steensma MR. In press. Anoikis-resistant subpopulations of human osteosarcoma display significant chemoresistance and are sensitive to targeted epigenetic therapies predicted by expression profiling.  J Trans Med. PubMed

Peacock JD, Dykema KJ, Toriello HV, Mooney MR, Scholten DJ 2nd, Winn ME, Borgman A, Duesbery NS, Hiemenga JA, Liu C, Campbell S, Nickoloff BP, Williams BO, Steensma MR. 2015. Oculoectodermal syndrome is a mosaic RASopathy associated with KRAS alterations.  Am J Med Genet 167(7):1429–1435          PubMed

Peacock JD, Dykema KJ, Toriello HV, Mooney MR, Scholten DJ 2nd, Winn ME, Borgman A, Duesbery NS, Hiemenga JA, Liu C, Campbell S, Nickoloff BP, Williams BO, Steensma MR. In press. Oculoectodermal syndrome is a mosaic RASopathy associated with KRAS alterations.  Am J Med Genet

Pelle DW, Peacock JD, Schmidt CL, Kampfschulte K, Scholten DJ 2nd, Russo SS, Easton KJ, Steensma MR. 2014. Genetic and functional studies of the intervertebral disc: A novel murine intervertebral disc model.  PLoS One 9(12)e112454.     PubMed     Article

Scholten DJ 2nd, Timmer CM, Peacock JD, Pelle DW, Williams BO, Steensma MR. 2014. Down regulation of Wnt signaling mitigates hypoxia-induced chemoresistance in human osteosarcoma cells.  PLoS One 9(10):e111431.     PubMed     Article

Puhaindran M, Schlumbohm S, Hamilton K, Rich M, Mitchell D, Steensma MR.  Radiation-induced osteosarcoma of the hand.  J Hand Surg Am 39(6):1151-1154.     PubMed     Article

Pelle DW, Ringler JW, Peacock JD, Kampfschulte K, Scholten II DJ, Davis MD, Mitchell DS, Steensma MR. Targeting receptor-activator nuclear kappa beta ligand in aneurysmal bone cysts: verification of target and therapeutic response.  Transl Res 164(2):139-148.     PubMed     Article

Peacock JD, Cherba D, Kampfschulte K, Smith MK, Monks NR, Webb CP, Steensma MR. 2013.  Molecular-guided therapy predictions reveal drug resistance phenotypes and treatment alternatives in malignant peripheral nerve sheath tumors.  J Transl Med 11(1):213.     PubMed      Article

Steensma MR, Tyler WK, Shaber AG, Goldring SR, Ross FP, Williams BO, Healey JH, Purdue PE.  2013.  Targeting the giant cell tumor stromal cell: functional characterization and a novel therapeutic strategy.  PLoS One 8(7): e69101.     PubMed     Article

Monks NR, Cherba DM, Kamerling SG, Simpson H, Rusk AW, Carter D, Eugster E, Mooney M, Sigler R, Steensma MR, Grabinski T, Marotti KR, Webb CP.  2013.  A multi-site feasibility study for personalized medicine in canines with osteosarcoma.  J Transl Med 11:158.     PubMed     Article

Valkenburg KC, Steensma MR, Williams BO, and Zhong Z.  2013.  Skeletal metastasis: treatments, mouse models, and the Wnt signaling.  Chin J Cancer 32(7):380–396.     PubMed      Article

Steensma MR, Healey JH.  2013.  Trends in the surgical treatment of pathologic proximal femur fractures among Musculoskeletal Tumor Society members.  Clin Orthop and Relat Res 471(6): 2000–2006.     PubMed      Article

Steensma MR, Morris C.  2013.  Ewing’s sarcoma.  In Orthopaedic Knowledge Update: Musculoskeletal Tumors 3, J. Sybil Biermann, ed.  Rosemont, IL: American Academy of Orthopaedic Surgeons.

Steensma MR, Boland PJ, Morris CD, Athanasian E, Healey JH.  2012.  Endoprosthetic treatment is more durable for pathologic proximal femur fractures.  Clin Orthop Relat Res 470(3):920-926.      PubMed     Article

Zhong Z, Williams BO, Steensma MR.  2012.  Commentary on “The activation of Beta-catenin by Gs contributes to the etiology of phenotypes seen in fibrous dysplasia and McCune–Albright syndrome”.  IBMS BoneKEy 9.     Article

Puhaindran M, Farooki A, Steensma MR, Hameed M, Healey JH, Boland PJ.  2011.  Atypical subtrochanteric femoral fractures in patients with skeletal malignant involvement treated with intravenous bisphosphonates.  J Bone Joint Surg Am 93(13):1235-1242.     PubMed     Article

Puhaindran M, Steensma MR, Athanasian E. 2010.  Partial hand preservation for large soft tissue sarcomas of the hand.  J Hand Surg Am 35(2):291-295.     PubMed     Article

Steensma MR, Jabara M, Anderson JG, Bohay DR.  2006.  Flexor hallucis longus tendon transfer for hallux claw toe deformity and vertical instability of the metatarsophalangeal joint.  Foot Ankle Int 27(9):689-692.     PubMed

Steensma MR, Anderson JG, Bohay DR.  2005.  Update on diseases and treatment of the peroneal tendon including peroneal tendon tear, subluxating peroneal tendon, and tendinosis.  Current Opinion in Orthopaedics 2:60-65.     Article